Small molecules which reverse obesity
Canned Analysis
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General Information
AccessionDCA00010431
TitleSmall molecules which reverse obesity
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the obesity gene expression signature in the neuroretina cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cb1ae467bea600fb8a42
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsaulc07
CREEDS IDdz:612
Cell Typeneuroretina
DO IDDOID:9970
Disease Nameobesity
Organismmouse
UMLS CUIC0028754
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1335288, GSM1335289, GSM1335290, GSM1335291
Perturbed SamplesGSM1335284, GSM1335285, GSM1335286, GSM1335287
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE55389
Gene Expression Omnibus
db/db model of obesity-induced type 2 diabetes: neuroretina
7
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