Small molecules which reverse cleft lip
Canned Analysis
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General Information
AccessionDCA00010449
TitleSmall molecules which reverse cleft lip
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the cleft lip gene expression signature in the dental pulp stem cell culture cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c3a2e467bea600fb8688
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsaulc07
CREEDS IDdz:618
Cell Typedental pulp stem cell culture
DO IDDOID:9296
Disease Namecleft lip
Organismhuman
UMLS CUIC0158651
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1045524, GSM1045525, GSM1045526, GSM1045527, GSM1045528, GSM1045529
Perturbed SamplesGSM1045517, GSM1045518, GSM1045519, GSM1045520, GSM1045521, GSM1045522, GSM1045523
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE42589
Gene Expression Omnibus
Non-syndromic cleft lip and palate: dental pulp stem cell cultures
7
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