Small molecules which reverse cystic fibrosis
Canned Analysis
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General Information
AccessionDCA00010465
TitleSmall molecules which reverse cystic fibrosis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the cystic fibrosis gene expression signature in the Intestinal Epithelium cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b6fae467bea600fb8054
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:65
Cell TypeIntestinal Epithelium
DO IDDOID:1485
Disease Namecystic fibrosis
Organismmouse
UMLS CUIC0010674
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM11902, GSM11903, GSM11904
Perturbed SamplesGSM11905, GSM11906, GSM11910
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE765
Gene Expression Omnibus
Cystic fibrosis and small intestine
12
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