Small molecules which mimic esophagus squamous cell carcinoma
Canned Analysis
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General Information
AccessionDCA00010478
TitleSmall molecules which mimic esophagus squamous cell carcinoma
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the esophagus squamous cell carcinoma gene expression signature in the KYSE human esophageal squamous cell carcinoma cell line and Normal esophageal tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cfe7e467bea600fb8c8c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:658
Cell TypeKYSE human esophageal squamous cell carcinoma cell line and Normal esophageal tissue
DO IDDOID:3748
Disease Nameesophagus squamous cell carcinoma
Organismhuman
UMLS CUIC0279626
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1560964, GSM1560965, GSM1560966
Perturbed SamplesGSM1560941, GSM1560942, GSM1560943, GSM1560944, GSM1560945, GSM1560946, GSM1560947, GSM1560948, GSM1560949
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE63941
Gene Expression Omnibus
Expression data from cultured human esophageal squamous cell carcinoma cell lines and cultured human fibroblasts.
7
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