Small molecules which reverse neurofibromatosis
Canned Analysis
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General Information
AccessionDCA00010505
TitleSmall molecules which reverse neurofibromatosis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the neurofibromatosis gene expression signature in the skeletal muscle (triceps) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b7ebe467bea600fb80c8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorlrallison
CREEDS IDdz:670
Cell Typeskeletal muscle (triceps)
DO IDDOID:8712
Disease Nameneurofibromatosis
Organismmouse
UMLS CUIC0220695
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM725364, GSM725365, GSM725366, GSM725367
Perturbed SamplesGSM725368, GSM725369, GSM725370, GSM725371
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE29343
Gene Expression Omnibus
Neurofibromin inactivation effect on triceps muscle
12
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