Small molecules which reverse facioscapulohumeral muscular dystrophy
Canned Analysis
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General Information
AccessionDCA00010507
TitleSmall molecules which reverse facioscapulohumeral muscular dystrophy
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the facioscapulohumeral muscular dystrophy gene expression signature in the bicep cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b7fae467bea600fb80d0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDdz:672
Cell Typebicep
DO IDDOID:11727
Disease Namefacioscapulohumeral muscular dystrophy
Organismhuman
UMLS CUIC0238288
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM892344, GSM892347, GSM892351, GSM892357, GSM892359, GSM892363, GSM892367, GSM892371, GSM892375, GSM892379, GSM892385, GSM892389
Perturbed SamplesGSM892342, GSM892345, GSM892349, GSM892353, GSM892355, GSM892361, GSM892365, GSM892369, GSM892373, GSM892377, GSM892381, GSM892383, GSM892387
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE36398
Gene Expression Omnibus
Facioscapulohumeral muscular dystrophy: bicep and deltoid muscles
14
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