Small molecules which reverse Duchenne muscular dystrophy
Canned Analysis
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General Information
AccessionDCA00010511
TitleSmall molecules which reverse Duchenne muscular dystrophy
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the Duchenne muscular dystrophy gene expression signature in the quadriceps cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b802e467bea600fb80d4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDdz:674
Cell Typequadriceps
DO IDDOID:11723
Disease NameDuchenne muscular dystrophy
Organismhuman
UMLS CUIC0013264
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM139501, GSM139502, GSM139503, GSM139504, GSM139505, GSM139506, GSM139507, GSM139508, GSM139509, GSM139510, GSM139511, GSM139512, GSM139513, GSM139514
Perturbed SamplesGSM139515, GSM139516, GSM139517, GSM139518, GSM139519, GSM139520, GSM139521, GSM139522, GSM139523, GSM139524, GSM139525, GSM139526, GSM139527, GSM139528, GSM139529, GSM139530, GSM139531, GSM139532, GSM139533, GSM139534, GSM139535, GSM139536, GSM139537
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE6011
Gene Expression Omnibus
Early-early stage Duchenne muscular dystrophy: quadriceps
7
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