Small molecules which mimic Emery-Dreifuss muscular dystrophy
Canned Analysis
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General Information
AccessionDCA00010514
TitleSmall molecules which mimic Emery-Dreifuss muscular dystrophy
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the Emery-Dreifuss muscular dystrophy gene expression signature in the whole heart cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cd53e467bea600fb8b58
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDdz:676
Cell Typewhole heart
DO IDDOID:11726
Disease NameEmery-Dreifuss muscular dystrophy
Organismmouse
UMLS CUIC0410189
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM147451, GSM147452, GSM147459, GSM147460, GSM147461, GSM147462, GSM147463, GSM147465
Perturbed SamplesGSM147506, GSM147507, GSM147509, GSM147510, GSM147511, GSM147512, GSM147513
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE8000
Gene Expression Omnibus
Lmna H222P homozygous and heterozygous mutant models of Emery-Dreifuss muscular dystrophy: hearts
19
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