Small molecules which reverse dilated cardiomyopathy
Canned Analysis
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General Information
AccessionDCA00010519
TitleSmall molecules which reverse dilated cardiomyopathy
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the dilated cardiomyopathy gene expression signature in the heart, left ventricle apex cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cd65e467bea600fb8b62
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDdz:678
Cell Typeheart, left ventricle apex
DO IDDOID:12930
Disease Namedilated cardiomyopathy
Organismhuman
UMLS CUIC0007193
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1053922, GSM1053929, GSM1053939, GSM1053940, GSM1053942
Perturbed SamplesGSM1053915, GSM1053917, GSM1053918, GSM1053919, GSM1053924, GSM1053925, GSM1053926, GSM1053933, GSM1053935, GSM1053937, GSM1053938, GSM1053941
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE42955
Gene Expression Omnibus
Dilated cardiomyopathy: left ventricle apex
14
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