Small molecules which reverse discoid lupus erythematosus
Canned Analysis
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General Information
AccessionDCA00010543
TitleSmall molecules which reverse discoid lupus erythematosus
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the discoid lupus erythematosus gene expression signature in the skin cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1bff8e467bea600fb84cc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDdz:689
Cell Typeskin
Disease Namediscoid lupus erythematosus
Organismhuman
UMLS CUIC0024138
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1267427, GSM1267428, GSM1267429, GSM1267430, GSM1267431, GSM1267432, GSM1267433, GSM1267434, GSM1267435, GSM1267436, GSM1267444, GSM1267445, GSM1267446
Perturbed SamplesGSM1267437, GSM1267438, GSM1267439, GSM1267440, GSM1267441, GSM1267442, GSM1267443
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE52471
Gene Expression Omnibus
Discoid lupus erythematosus and psoriasis skin biopsies
14
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