Small molecules which mimic psoriasis
Canned Analysis
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General Information
AccessionDCA00010544
TitleSmall molecules which mimic psoriasis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the psoriasis gene expression signature in the skin cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cc89e467bea600fb8af4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDdz:690
Cell Typeskin
DO IDDOID:8893
Disease Namepsoriasis
Organismhuman
UMLS CUIC0033860
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1267427, GSM1267428, GSM1267429, GSM1267430, GSM1267431, GSM1267432, GSM1267433, GSM1267434, GSM1267435, GSM1267436, GSM1267444, GSM1267445, GSM1267446
Perturbed SamplesGSM1267412, GSM1267413, GSM1267414, GSM1267415, GSM1267416, GSM1267417, GSM1267418, GSM1267419, GSM1267420, GSM1267421, GSM1267422, GSM1267423, GSM1267424, GSM1267425, GSM1267426, GSM1267447, GSM1267448, GSM1267449
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE52471
Gene Expression Omnibus
Discoid lupus erythematosus and psoriasis skin biopsies
14
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