Small molecules which reverse systemic lupus erythematosus
Canned Analysis
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General Information
AccessionDCA00010549
TitleSmall molecules which reverse systemic lupus erythematosus
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the systemic lupus erythematosus gene expression signature in the CD4+ T cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cc74e467bea600fb8aea
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDdz:692
Cell TypeCD4+ T cells
DO IDDOID:9074
Disease Namesystemic lupus erythematosus
Organismhuman
UMLS CUIC0024141
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM260886, GSM260889, GSM260891, GSM260894, GSM260897, GSM260900, GSM260903, GSM260906, GSM260909
Perturbed SamplesGSM260914, GSM260916, GSM260919, GSM260922, GSM260925, GSM260927, GSM260930, GSM260933, GSM260936, GSM260939, GSM260942, GSM260945, GSM260948, GSM260950
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10325
Gene Expression Omnibus
Systemic Lupus Erythematosus: mononuclear cells
21
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