Small molecules which mimic psoriasis
Canned Analysis
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General Information
AccessionDCA00010558
TitleSmall molecules which mimic psoriasis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the psoriasis gene expression signature in the Whole blood (Cutaneous Psoriasis) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cc29e467bea600fb8ac4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:697
Cell TypeWhole blood (Cutaneous Psoriasis)
DO IDDOID:8893
Disease Namepsoriasis
Organismhuman
UMLS CUIC0033860
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1501552, GSM1501553, GSM1501554, GSM1501555, GSM1501556, GSM1501557, GSM1501558, GSM1501559, GSM1501560, GSM1501561, GSM1501562, GSM1501563
Perturbed SamplesGSM1501532, GSM1501533, GSM1501534, GSM1501535, GSM1501536, GSM1501537, GSM1501538, GSM1501539, GSM1501540, GSM1501541, GSM1501542, GSM1501543, GSM1501544, GSM1501545, GSM1501546, GSM1501547, GSM1501548, GSM1501549, GSM1501550, GSM1501551
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE61281
Gene Expression Omnibus
Human Whole Blood: Psoriatic Arthritis [PsA] vs. Cutaneous Psoriasis Without Arthritis [PsC] vs. Controls
14
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