Small molecules which reverse pancreatic ductal adenocarcinoma
Canned Analysis
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General Information
AccessionDCA00010563
TitleSmall molecules which reverse pancreatic ductal adenocarcinoma
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the pancreatic ductal adenocarcinoma gene expression signature in the Pancreatic tumor cells (bitransgenic Pdx1-cre/Kras*A MICE) and Pancreatic cells (WT MICE) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b902e467bea600fb8154
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:699
Cell TypePancreatic tumor cells (bitransgenic Pdx1-cre/Kras*A MICE) and Pancreatic cells (WT MICE)
DO IDDOID:3498
Disease Namepancreatic ductal adenocarcinoma
Organismmouse
UMLS CUIC1335302
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1298160, GSM1298161, GSM1298162, GSM1298163, GSM1298164
Perturbed SamplesGSM1298154, GSM1298155, GSM1298156, GSM1298157, GSM1298158, GSM1298159
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE53659
Gene Expression Omnibus
Expression data from WT mice and bitransgenic Pdx1-cre/Kras*A mice bearing Pancreatic Ductal Adenocarcinoma
7
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