Small molecules which mimic Huntington's disease
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00010606
TitleSmall molecules which mimic Huntington's disease
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the Huntington's disease gene expression signature in the striatum cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c846e467bea600fb88d6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorlrallison
CREEDS IDdz:721
Cell Typestriatum
DO IDDOID:12858
Disease NameHuntington's disease
Organismmouse
UMLS CUIC0020179
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM135225, GSM135226, GSM135227
Perturbed SamplesGSM135217, GSM135219, GSM135221
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5786
Gene Expression Omnibus
PGC-1alpha transcriptional coactivator null mutation effect on the brain striatum
12
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.