Small molecules which reverse hepatocellular carcinoma
Canned Analysis
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General Information
AccessionDCA00010633
TitleSmall molecules which reverse hepatocellular carcinoma
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the hepatocellular carcinoma gene expression signature in the Peripheral blood mononuclear cell cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c67be467bea600fb87f0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:735
Cell TypePeripheral blood mononuclear cell
DO IDDOID:684
Disease Namehepatocellular carcinoma
Organismhuman
UMLS CUIC0279607
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1403331, GSM1403332, GSM1403333, GSM1403334, GSM1403335
Perturbed SamplesGSM1403309, GSM1403310, GSM1403311, GSM1403312, GSM1403313, GSM1403314, GSM1403315, GSM1403316, GSM1403317, GSM1403318
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE58208
Gene Expression Omnibus
Gene expression profiling of PBMC from normal individuals, chronic hepatitis B carriers and hepatocellular carcinoma patients
14
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