Small molecules which reverse hepatitis C virus related hepatocellular carcinoma
Canned Analysis
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General Information
AccessionDCA00010635
TitleSmall molecules which reverse hepatitis C virus related hepatocellular carcinoma
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the hepatitis C virus related hepatocellular carcinoma gene expression signature in the Peripheral blood mononuclear cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c682e467bea600fb87f4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:736
Cell TypePeripheral blood mononuclear cells
Disease Namehepatitis C virus related hepatocellular carcinoma
Organismhuman
UMLS CUIC1333978
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1403331, GSM1403332, GSM1403333, GSM1403334, GSM1403335
Perturbed SamplesGSM1403319, GSM1403320, GSM1403321, GSM1403322, GSM1403323, GSM1403324, GSM1403325, GSM1403326, GSM1403327, GSM1403328, GSM1403329, GSM1403330
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE58208
Gene Expression Omnibus
Gene expression profiling of PBMC from normal individuals, chronic hepatitis B carriers and hepatocellular carcinoma patients
14
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