Small molecules which mimic multiple sclerosis
Canned Analysis
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General Information
AccessionDCA00010636
TitleSmall molecules which mimic multiple sclerosis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the multiple sclerosis gene expression signature in the brain lesion (MS after demyelination - active inflammation) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c688e467bea600fb87f6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:737
Cell Typebrain lesion (MS after demyelination - active inflammation)
DO IDDOID:2377
Disease Namemultiple sclerosis
Organismhuman
UMLS CUIC0026769
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM931812, GSM931813
Perturbed SamplesGSM931815, GSM931816
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE38010
Gene Expression Omnibus
Multiple sclerosis: brain lesions
14
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