Small molecules which reverse multiple sclerosis
Canned Analysis
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General Information
AccessionDCA00010645
TitleSmall molecules which reverse multiple sclerosis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the multiple sclerosis gene expression signature in the peripheral blood mononuclear cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c56ae467bea600fb8768
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:743
Cell Typeperipheral blood mononuclear cells
DO IDDOID:2377
Disease Namemultiple sclerosis
Organismhuman
UMLS CUIC0026769
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM545818, GSM545819, GSM545820, GSM545821, GSM545822, GSM545823, GSM545824, GSM545825, GSM545826, GSM545827, GSM545828, GSM545829, GSM545830, GSM545831, GSM545832
Perturbed SamplesGSM545833, GSM545834, GSM545835, GSM545836, GSM545837, GSM545838, GSM545839, GSM545840, GSM545841, GSM545842, GSM545843, GSM545844, GSM545845, GSM545846
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE21942
Gene Expression Omnibus
Multiple sclerosis: peripheral blood mononuclear cells
7
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