Small molecules which reverse psoriasis
Canned Analysis
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General Information
AccessionDCA00010667
TitleSmall molecules which reverse psoriasis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the psoriasis gene expression signature in the Non-lesional skin cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b9d0e467bea600fb81b8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:754
Cell TypeNon-lesional skin
DO IDDOID:8893
Disease Namepsoriasis
Organismhuman
UMLS CUIC0033860
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM372286, GSM372287, GSM372288, GSM372289, GSM372290, GSM372291, GSM372292, GSM372293, GSM372294, GSM372295, GSM372296, GSM372297, GSM372298, GSM372299, GSM372300, GSM372301, GSM372302, GSM372303, GSM372304, GSM372305, GSM372306
Perturbed SamplesGSM372307, GSM372309, GSM372311, GSM372313, GSM372315, GSM372317, GSM372319, GSM372321, GSM372323, GSM372326, GSM372328, GSM372330, GSM372332, GSM372335, GSM372337, GSM372339, GSM372341, GSM372343, GSM372345, GSM372347, GSM372349, GSM372351, GSM372353, GS
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE14905
Gene Expression Omnibus
Psoriasis
14
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