Small molecules which reverse gastrointestinal stromal tumor
Canned Analysis
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General Information
AccessionDCA00010673
TitleSmall molecules which reverse gastrointestinal stromal tumor
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gastrointestinal stromal tumor gene expression signature in the Gastric Tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b8d2e467bea600fb813c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:76
Cell TypeGastric Tissue
DO IDDOID:9253
Disease Namegastrointestinal stromal tumor
Organismhuman
UMLS CUIC0238198
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM400206, GSM400208, GSM400210, GSM400212, GSM400214, GSM400220, GSM400226, GSM400227, GSM400228, GSM400230, GSM400232, GSM400240, GSM400241, GSM400242, GSM400246, GSM400251, GSM400252, GSM400258
Perturbed SamplesGSM400216, GSM400218, GSM400222, GSM400224, GSM400234, GSM400236, GSM400238, GSM400245, GSM400248, GSM400255
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE15966
Gene Expression Omnibus
Gene expression signature predictive of rapid response to imatinib mesylate in Gastrointestinal Stromal Tumor (GIST)
7
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