Small molecules which mimic atherosclerosis
Canned Analysis
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General Information
AccessionDCA00010674
TitleSmall molecules which mimic atherosclerosis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the atherosclerosis gene expression signature in the Aorta Smooth Muscle Tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b8d7e467bea600fb813e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:77
Cell TypeAorta Smooth Muscle Tissue
DO IDDOID:1936
Disease Nameatherosclerosis
Organismmouse
UMLS CUIC0004153
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM26750, GSM26756, GSM26762, GSM26763, GSM26764, GSM26781, GSM26782, GSM26783, GSM26784, GSM26785, GSM26795, GSM26796, GSM26797, GSM26798, GSM26799
Perturbed SamplesGSM26765, GSM26766, GSM26767, GSM26768, GSM26774, GSM26775, GSM26776, GSM26777, GSM26791, GSM26792, GSM26793, GSM26794
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1560
Gene Expression Omnibus
High fat diet effect on aorta: time course
7
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