Small molecules which reverse acute myeloid leukemia
Canned Analysis
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General Information
AccessionDCA00010697
TitleSmall molecules which reverse acute myeloid leukemia
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the acute myeloid leukemia gene expression signature in the Bone marrow cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cea3e467bea600fb8bfe
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:782
Cell TypeBone marrow
DO IDDOID:9119
Disease Nameacute myeloid leukemia
Organismhuman
UMLS CUIC0023467
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM239323, GSM239324, GSM239326, GSM239328, GSM239329, GSM239331, GSM239332, GSM239333, GSM239334, GSM239335
Perturbed SamplesGSM239371, GSM239487, GSM239489, GSM239492, GSM239497, GSM239520, GSM240427
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE9476
Gene Expression Omnibus
Acute myeloid leukemia
14
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