Small molecules which reverse acute myeloid leukemia
Canned Analysis
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General Information
AccessionDCA00010699
TitleSmall molecules which reverse acute myeloid leukemia
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the acute myeloid leukemia gene expression signature in the Peripheral blood cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cfa3e467bea600fb8c6e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:783
Cell TypePeripheral blood
DO IDDOID:9119
Disease Nameacute myeloid leukemia
Organismhuman
UMLS CUIC0023467
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM240430, GSM240431, GSM240432, GSM240433, GSM240494, GSM240495, GSM240496, GSM240497, GSM240498, GSM240499
Perturbed SamplesGSM239345, GSM239346, GSM239348, GSM239363, GSM239460, GSM239485, GSM239488, GSM239490, GSM239491, GSM239493, GSM239494, GSM239495, GSM239496, GSM239498, GSM239516, GSM239580, GSM240405, GSM240406, GSM240429
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE9476
Gene Expression Omnibus
Acute myeloid leukemia
14
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