Small molecules which mimic Huntington's disease
Canned Analysis
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General Information
AccessionDCA00010712
TitleSmall molecules which mimic Huntington's disease
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the Huntington's disease gene expression signature in the Peripheral blood expression profile - symptomatic patients (HG-U133A) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c34fe467bea600fb8662
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:795
Cell TypePeripheral blood expression profile - symptomatic patients (HG-U133A)
DO IDDOID:12858
Disease NameHuntington's disease
Organismhuman
UMLS CUIC0020179
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM30580, GSM30581, GSM30582, GSM30583, GSM30584, GSM30585, GSM30586, GSM30587, GSM30588, GSM30589, GSM30590, GSM30591, GSM30592, GSM30593
Perturbed SamplesGSM30530, GSM30531, GSM30532, GSM30533, GSM30534, GSM30535, GSM30536, GSM30537, GSM30538, GSM30539, GSM30540, GSM30541
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1751
Gene Expression Omnibus
Huntington's disease: peripheral blood expression profile (HG-U133A)
14
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