Small molecules which reverse diabetes mellitus
Canned Analysis
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General Information
AccessionDCA00010731
TitleSmall molecules which reverse diabetes mellitus
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the diabetes mellitus gene expression signature in the beta cells of pancreas cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ba58e467bea600fb81fc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgaribr01
CREEDS IDdz:805
Cell Typebeta cells of pancreas
DO IDDOID:9351
Disease Namediabetes mellitus
Organismmouse
UMLS CUIC0011849
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM771025, GSM771026, GSM771027
Perturbed SamplesGSM771022, GSM771023, GSM771024
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE31150
Gene Expression Omnibus
Raf kinase inhibitor 1 knockout effect on C57BL/6 pancreas
17
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