Small molecules which reverse polycystic ovary syndrome
Canned Analysis
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General Information
AccessionDCA00010757
TitleSmall molecules which reverse polycystic ovary syndrome
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the polycystic ovary syndrome gene expression signature in the Cumulus cells cultured (Obese patients) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b58ae467bea600fb7ff4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:826
Cell TypeCumulus cells cultured (Obese patients)
DO IDDOID:11612
Disease Namepolycystic ovary syndrome
Organismhuman
UMLS CUIC0032460
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM277444, GSM277445, GSM277446, GSM277447, GSM277448
Perturbed SamplesGSM277454, GSM277455, GSM277456, GSM277457, GSM277458, GSM277459, GSM277460
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE10946
Gene Expression Omnibus
Lean and overweight-obese polycystic ovary syndrome patients: cultured cumulus cells
14
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