Small molecules which mimic prostate cancer
Canned Analysis
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General Information
AccessionDCA00010766
TitleSmall molecules which mimic prostate cancer
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the prostate cancer gene expression signature in the Radical prostatectomy tissue samples (TMPRSS2:ERG gene fusion POSITIVE) and Benign prostate tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c098e467bea600fb851a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:834
Cell TypeRadical prostatectomy tissue samples (TMPRSS2:ERG gene fusion POSITIVE) and Benign prostate tissue
DO IDDOID:10283
Disease Nameprostate cancer
Organismhuman
UMLS CUIC0376358
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1348946, GSM1348947, GSM1348948, GSM1348949, GSM1348950, GSM1348951, GSM1348952, GSM1348953
Perturbed SamplesGSM1348940, GSM1348941, GSM1348942, GSM1348943, GSM1348944, GSM1348945
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE55945
Gene Expression Omnibus
Prostate cancer
14
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