Small molecules which reverse prostate cancer
Canned Analysis
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General Information
AccessionDCA00010769
TitleSmall molecules which reverse prostate cancer
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the prostate cancer gene expression signature in the Radical prostatectomy tissue samples (TMPRSS2:ERG gene fusion NEGATIVE) and Benign prostate tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c093e467bea600fb8518
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:835
Cell TypeRadical prostatectomy tissue samples (TMPRSS2:ERG gene fusion NEGATIVE) and Benign prostate tissue
DO IDDOID:10283
Disease Nameprostate cancer
Organismhuman
UMLS CUIC0376358
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1348946, GSM1348947, GSM1348948, GSM1348949, GSM1348950, GSM1348951, GSM1348952, GSM1348953
Perturbed SamplesGSM1348933, GSM1348934, GSM1348935, GSM1348936, GSM1348937, GSM1348938, GSM1348939
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE55945
Gene Expression Omnibus
Prostate cancer
14
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