Small molecules which reverse idiopathic pulmonary fibrosis
Canned Analysis
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General Information
AccessionDCA00010799
TitleSmall molecules which reverse idiopathic pulmonary fibrosis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the idiopathic pulmonary fibrosis gene expression signature in the Lung fibroblasts (Rapid progressing fibrosis) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c411e467bea600fb86bc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:850
Cell TypeLung fibroblasts (Rapid progressing fibrosis)
DO IDDOID:0050156
Disease Nameidiopathic pulmonary fibrosis
Organismhuman
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1089616, GSM1089617, GSM1089618, GSM1089620
Perturbed SamplesGSM1089614, GSM1089619, GSM1089622, GSM1089623
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE44723
Gene Expression Omnibus
Idiopathic pulmonary fibrosis: cultured lung fibroblasts
14
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