Small molecules which mimic schizophrenia
Canned Analysis
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General Information
AccessionDCA00010802
TitleSmall molecules which mimic schizophrenia
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the schizophrenia gene expression signature in the Anterior prefrontal cortex - postmortem - Female cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c41fe467bea600fb86c2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:852
Cell TypeAnterior prefrontal cortex - postmortem - Female
DO IDDOID:5419
Disease Nameschizophrenia
Organismhuman
UMLS CUIC0220702
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM439780, GSM439783, GSM439787, GSM439792, GSM439802, GSM439808, GSM439810, GSM439812, GSM439818, GSM439825, GSM439826
Perturbed SamplesGSM439781, GSM439790, GSM439795, GSM439800, GSM439805, GSM439807, GSM439811, GSM439820, GSM439827
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE17612
Gene Expression Omnibus
Schizophrenia: postmortem anterior prefrontal cortex
14
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