Small molecules which reverse schizophrenia
Canned Analysis
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General Information
AccessionDCA00010805
TitleSmall molecules which reverse schizophrenia
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the schizophrenia gene expression signature in the Anterior prefrontal cortex - postmortem - Male cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c419e467bea600fb86c0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:853
Cell TypeAnterior prefrontal cortex - postmortem - Male
DO IDDOID:5419
Disease Nameschizophrenia
Organismhuman
UMLS CUIC0220702
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM439779, GSM439782, GSM439788, GSM439789, GSM439793, GSM439797, GSM439799, GSM439804, GSM439814, GSM439816, GSM439819, GSM439822
Perturbed SamplesGSM439778, GSM439784, GSM439785, GSM439786, GSM439791, GSM439794, GSM439796, GSM439798, GSM439801, GSM439803, GSM439806, GSM439809, GSM439813, GSM439815, GSM439817, GSM439821, GSM439823, GSM439824, GSM439828
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE17612
Gene Expression Omnibus
Schizophrenia: postmortem anterior prefrontal cortex
14
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