Small molecules which mimic Ischemic stroke
Canned Analysis
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General Information
AccessionDCA00010810
TitleSmall molecules which mimic Ischemic stroke
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the Ischemic stroke gene expression signature in the Peripheral blood mononuclear cells (collected from IS patients at least 6 months after the first and only stroke event) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c43fe467bea600fb86d2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:856
Cell TypePeripheral blood mononuclear cells (collected from IS patients at least 6 months after the first and only stroke event)
Disease NameIschemic stroke
Organismhuman
UMLS CUIC0948008
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM554014, GSM554015, GSM554016, GSM554017, GSM554018, GSM554019, GSM554020, GSM554021, GSM554022, GSM554023, GSM554024, GSM554025, GSM554026, GSM554027, GSM554028, GSM554029, GSM554030, GSM554031, GSM554032, GSM554033
Perturbed SamplesGSM554034, GSM554035, GSM554036, GSM554037, GSM554038, GSM554039, GSM554040, GSM554041, GSM554042, GSM554043, GSM554044, GSM554045, GSM554046, GSM554047, GSM554048, GSM554049, GSM554050, GSM554051, GSM554052, GSM554053
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE22255
Gene Expression Omnibus
Ischemic stroke: peripheral blood mononuclear cells
7
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