Small molecules which mimic adrenoleukodystrophy
Canned Analysis
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General Information
AccessionDCA00010822
TitleSmall molecules which mimic adrenoleukodystrophy
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the adrenoleukodystrophy gene expression signature in the Dermal fibroblast (from childhood cerebral adrenoleukodystrophy (CCALD) patient) and healthy fibroblasts cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c5dfe467bea600fb87a2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:864
Cell TypeDermal fibroblast (from childhood cerebral adrenoleukodystrophy (CCALD) patient) and healthy fibroblasts
DO IDDOID:10588
Disease Nameadrenoleukodystrophy
Organismhuman
UMLS CUIC0162309
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM847088, GSM847089, GSM847090
Perturbed SamplesGSM847091, GSM847092
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE34309
Gene Expression Omnibus
Childhood cerebral adrenoleukodystrophy patient-specific iPSC model
14
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