Small molecules which reverse schizophrenia
Canned Analysis
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General Information
AccessionDCA00010865
TitleSmall molecules which reverse schizophrenia
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the schizophrenia gene expression signature in the Induced pluripotent stem cell-derived neurons - Male cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ccb5e467bea600fb8b0a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:891
Cell TypeInduced pluripotent stem cell-derived neurons - Male
DO IDDOID:5419
Disease Nameschizophrenia
Organismhuman
UMLS CUIC0220702
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM630785, GSM630786, GSM630787
Perturbed SamplesGSM630797, GSM630798, GSM630799, GSM630803, GSM630804, GSM630805, GSM630806, GSM630807, GSM630808
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE25673
Gene Expression Omnibus
Induced pluripotent stem cell-derived neurons from schizophrenia patients
14
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