Small molecules which mimic schizophrenia
Canned Analysis
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General Information
AccessionDCA00010866
TitleSmall molecules which mimic schizophrenia
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the schizophrenia gene expression signature in the Induced pluripotent stem cell-derived neurons - Female cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cccae467bea600fb8b14
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:892
Cell TypeInduced pluripotent stem cell-derived neurons - Female
DO IDDOID:5419
Disease Nameschizophrenia
Organismhuman
UMLS CUIC0220702
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM630788, GSM630789, GSM630790, GSM630791, GSM630792, GSM630793, GSM630794, GSM630795, GSM630796
Perturbed SamplesGSM630800, GSM630801, GSM630802
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE25673
Gene Expression Omnibus
Induced pluripotent stem cell-derived neurons from schizophrenia patients
14
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