Small molecules which mimic type 1 diabetes mellitus
Canned Analysis
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General Information
AccessionDCA00010872
TitleSmall molecules which mimic type 1 diabetes mellitus
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the type 1 diabetes mellitus gene expression signature in the T lymphocyte cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1bdaee467bea600fb83a6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:9
Cell TypeT lymphocyte
DO IDDOID:9744
Disease Nametype 1 diabetes mellitus
Organismhuman
UMLS CUIC0011854
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM266963, GSM266964, GSM266965, GSM266966, GSM266967, GSM266968, GSM266969, GSM266970, GSM266971, GSM266972, GSM266973, GSM266974, GSM266975, GSM266976, GSM266977
Perturbed SamplesGSM266978, GSM266979, GSM266980, GSM266981, GSM266982, GSM266983, GSM266984, GSM266985, GSM266986, GSM266987, GSM266988, GSM266989
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10586
Gene Expression Omnibus
Expression data from recent-onset T1D patients and controls
7
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