Small molecules which reverse rheumatoid arthritis
Canned Analysis
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General Information
AccessionDCA00010877
TitleSmall molecules which reverse rheumatoid arthritis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the rheumatoid arthritis gene expression signature in the Peripheral blood mononuclear cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1b861e467bea600fb8104
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:904
Cell TypePeripheral blood mononuclear cells
DO IDDOID:7148
Disease Namerheumatoid arthritis
Organismhuman
UMLS CUIC0003873
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM389705, GSM389707, GSM389709, GSM389710, GSM389712, GSM389713, GSM389715, GSM389718, GSM389720, GSM389723, GSM389725, GSM389728, GSM389729, GSM389732, GSM389734
Perturbed SamplesGSM389703, GSM389704, GSM389706, GSM389708, GSM389711, GSM389714, GSM389716, GSM389717, GSM389719, GSM389721, GSM389722, GSM389724, GSM389726, GSM389727, GSM389730, GSM389731, GSM389733, GSM389735
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15573
Gene Expression Omnibus
Rheumatoid arthritis: peripheral blood mononuclear cells
7
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