Small molecules which mimic Huntington's disease
Canned Analysis
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General Information
AccessionDCA00010914
TitleSmall molecules which mimic Huntington's disease
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the Huntington's disease gene expression signature in the striatal cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cf58e467bea600fb8c4c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:929
Cell Typestriatal cells
DO IDDOID:12858
Disease NameHuntington's disease
Organismmouse
UMLS CUIC0020179
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM82444, GSM82445, GSM82446
Perturbed SamplesGSM82447, GSM82448, GSM82449
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE3583
Gene Expression Omnibus
Huntington's disease models
12
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