Small molecules which mimic Huntington's disease
Canned Analysis
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General Information
AccessionDCA00010916
TitleSmall molecules which mimic Huntington's disease
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the Huntington's disease gene expression signature in the Lymphocytes from patients with moderate stage Huntington's disease - Male cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c19de467bea600fb8592
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:930
Cell TypeLymphocytes from patients with moderate stage Huntington's disease - Male
DO IDDOID:12858
Disease NameHuntington's disease
Organismhuman
UMLS CUIC0020179
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM217771, GSM217772, GSM217773, GSM217774, GSM217775
Perturbed SamplesGSM217784, GSM217785, GSM217786, GSM217787
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8762
Gene Expression Omnibus
Moderate stage Huntington's disease lymphocytes
21
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