Small molecules which reverse Parkinson's disease
Canned Analysis
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General Information
AccessionDCA00010921
TitleSmall molecules which reverse Parkinson's disease
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the Parkinson's disease gene expression signature in the Substantia nigra - Male cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c008e467bea600fb84d4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:940
Cell TypeSubstantia nigra - Male
DO IDDOID:14330
Disease NameParkinson's disease
Organismhuman
UMLS CUIC0030567
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM184355, GSM184360, GSM184361, GSM184362
Perturbed SamplesGSM184363, GSM184364, GSM184365, GSM184366, GSM184367, GSM184369, GSM184370, GSM184372, GSM184373, GSM184375, GSM184376, GSM184377, GSM184378
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE7621
Gene Expression Omnibus
Parkinson's disease: substantia nigra
14
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