Small molecules which reverse osteoarthritis
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00010925
TitleSmall molecules which reverse osteoarthritis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the osteoarthritis gene expression signature in the Articular CONDROCYTES from osteoarthritic knees of Sprague-Dawley males and Sham control cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c000e467bea600fb84d0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:943
Cell TypeArticular CONDROCYTES from osteoarthritic knees of Sprague-Dawley males and Sham control
DO IDDOID:8398
Disease Nameosteoarthritis
Organismrat
UMLS CUIC0157946
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM200584, GSM200593, GSM200594, GSM200595, GSM200596
Perturbed SamplesGSM199973, GSM200585, GSM200586, GSM200587, GSM200588
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE8077
Gene Expression Omnibus
Knee osteoarthritis model: chondrocytes
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.