Small molecules which reverse Intestinal polyposis
Canned Analysis
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General Information
AccessionDCA00010939
TitleSmall molecules which reverse Intestinal polyposis
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the Intestinal polyposis gene expression signature in the Intestinal POLYPS model (generated by the deletion of the phosphatase PTEN gene from the intestine) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1bdffe467bea600fb83d0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:952
Cell TypeIntestinal POLYPS model (generated by the deletion of the phosphatase PTEN gene from the intestine)
Disease NameIntestinal polyposis
Organismmouse
UMLS CUIC1257915
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM140792, GSM140816
Perturbed SamplesGSM140813, GSM140817, GSM140818
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6078
Gene Expression Omnibus
Intestinal polyposis model
12
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