Small molecules which mimic multiple myeloma
Canned Analysis
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General Information
AccessionDCA00010942
TitleSmall molecules which mimic multiple myeloma
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the multiple myeloma gene expression signature in the B cells - derived from the spleen (MM model XBP-1s overexpression) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1cefce467bea600fb8c24
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:955
Cell TypeB cells - derived from the spleen (MM model XBP-1s overexpression)
DO IDDOID:9538
Disease Namemultiple myeloma
Organismmouse
UMLS CUIC0026764
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM160730, GSM160731, GSM160739, GSM160860, GSM160861
Perturbed SamplesGSM160869, GSM160880, GSM160881, GSM160882, GSM160883, GSM160884
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE6980
Gene Expression Omnibus
Multiple myeloma model
14
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