Small molecules which mimic progeria
Canned Analysis
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General Information
AccessionDCA00010958
TitleSmall molecules which mimic progeria
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the progeria gene expression signature in the liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1c728e467bea600fb8846
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDdz:984
Cell Typeliver
DO IDDOID:3911
Disease Nameprogeria
Organismmouse
UMLS CUIC0033300
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM808406, GSM808407, GSM808408
Perturbed SamplesGSM808403, GSM808404, GSM808405
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE32609
Gene Expression Omnibus
Lmna G609G knock-in model of Hutchinson-Gilford Progeria Syndrome: liver
12
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