Enrichment analysis of genes dysregulated in Down syndrome
Canned Analysis
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General Information
AccessionDCA00011017
TitleEnrichment analysis of genes dysregulated in Down syndrome
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between cells affected by Down syndrome and healthy control cells in the fibroblast cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3086697
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdz:1060
Cell Typefibroblast
DO IDDOID:14250
Disease NameDown syndrome
Organismhuman
UMLS CUIC0013080
Characteristic Direction parameters
Control SamplesGSM1053952, GSM1053953, GSM1053954, GSM1053955, GSM1053956, GSM1053957, GSM1053961, GSM1053962, GSM1053963, GSM1053976, GSM1053977, GSM1053978, GSM1053979, GSM1053980, GSM1053981
Perturbed SamplesGSM1053958, GSM1053959, GSM1053960, GSM1053982, GSM1053983, GSM1053984
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE42956
Gene Expression Omnibus
Integration-Free Induced Pluripotent Stem Cells Model Genetic and Neural Developmental Features of Down Syndrome Etiology
14
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