Enrichment analysis of genes dysregulated in sickle cell anemia
Canned Analysis
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General Information
AccessionDCA00011034
TitleEnrichment analysis of genes dysregulated in sickle cell anemia
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between cells affected by sickle cell anemia and healthy control cells in the Endothelial cell cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3085194
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:109
Cell TypeEndothelial cell
DO IDDOID:10923
Disease Namesickle cell anemia
Organismhuman
UMLS CUIC0002895
Characteristic Direction parameters
Control SamplesGSM249425, GSM249426, GSM249427, GSM249428, GSM249429, GSM249430, GSM249431, GSM249432, GSM249433, GSM249434, GSM249435, GSM249436, GSM249437, GSM249438, GSM249439, GSM249440, GSM249441, GSM249442, GSM249443, GSM249444, GSM249445, GSM249446, GSM249447, GS
Perturbed SamplesGSM249452, GSM249453, GSM249454, GSM249455, GSM249456, GSM249457, GSM249458, GSM249459, GSM249460, GSM249461, GSM249462, GSM249463, GSM249464, GSM249465, GSM249466, GSM249467, GSM249468, GSM249469, GSM249470, GSM249471
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE9877
Gene Expression Omnibus
Genetic Endothelial Systems Biology of Sickle Stroke Risk
7
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