Enrichment analysis of genes dysregulated in Down syndrome
Canned Analysis
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General Information
AccessionDCA00011455
TitleEnrichment analysis of genes dysregulated in Down syndrome
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between cells affected by Down syndrome and healthy control cells in the soleus muscle, in the basal state, from five-month-old Ts65Dn Down syndrome (DS) males cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3085882
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatornbongio
CREEDS IDdz:529
Cell Typesoleus muscle, in the basal state, from five-month-old Ts65Dn Down syndrome (DS) males
DO IDDOID:14250
Disease NameDown syndrome
Organismmouse
UMLS CUIC0013080
Characteristic Direction parameters
Control SamplesGSM957176, GSM957177, GSM957178, GSM957179
Perturbed SamplesGSM957172, GSM957173, GSM957174, GSM957175
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE39159
Gene Expression Omnibus
Ts65Dn aneuploidy model of Down syndrome: skeletal muscle
7
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