Enrichment analysis of genes dysregulated in precursor B lymphoblastic lymphoma/leukemia
Canned Analysis
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General Information
AccessionDCA00011672
TitleEnrichment analysis of genes dysregulated in precursor B lymphoblastic lymphoma/leukemia
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between cells affected by precursor B lymphoblastic lymphoma/leukemia and healthy control cells in the AT2 E/R positive BCP ALL cell line (following E/R -ETV6/RUNX1- knockdown) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3084976
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:803
Cell TypeAT2 E/R positive BCP ALL cell line (following E/R -ETV6/RUNX1- knockdown)
DO IDDOID:7061
Disease Nameprecursor B lymphoblastic lymphoma/leukemia
Organismhuman
UMLS CUIC0862030
Characteristic Direction parameters
Control SamplesGSM734473, GSM734475
Perturbed SamplesGSM734474, GSM734476
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE29639
Gene Expression Omnibus
Leukemia-specific fusion gene ETV6/RUNX1 knockdown effect on ETV6/RUNX1-positive, B-cell precursor acute lymphoblastic leukemia cell lines
14
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