Enrichment analysis of genes dysregulated in relapsing-remitting multiple sclerosis
Canned Analysis
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General Information
AccessionDCA00011734
TitleEnrichment analysis of genes dysregulated in relapsing-remitting multiple sclerosis
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between cells affected by relapsing-remitting multiple sclerosis and healthy control cells in the CD4+ T cells Lymphocytes (sorted from PBMCs from monozygotic twin pairs discordant for RRMS) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3086269
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:879
Cell TypeCD4+ T cells Lymphocytes (sorted from PBMCs from monozygotic twin pairs discordant for RRMS)
DO IDDOID:2378
Disease Namerelapsing-remitting multiple sclerosis
Organismhuman
UMLS CUIC0751967
Characteristic Direction parameters
Control SamplesGSM413790, GSM413792, GSM413795, GSM413796
Perturbed SamplesGSM413791, GSM413793, GSM413794, GSM413797
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE16461
Gene Expression Omnibus
Identical twins discordant for Multiple sclerosis: CD4+ and CD8+ T cells
7
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